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Evidence is increasing that addiction without exception is related to difficulty with the brain's reward center, particularly the mesolimbic system. This area of the problem regulates reward responses in getting food and sex, plus in nurturing infants and children. One of the most important neurotransmitters involved in reward responses, both when they malfunction and after they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the quantity of dopamine released in in reaction to a stimulus"(Bostwick & Bucci, 2008).
Using two separate drugs to lose weight naturally can be very effective you can find combinations before the FDA now awaiting approval. When dealing with fat loss and the people who go through it one should err on the side of caution and allow FDA do its job and demand some research be done so that the public is aware of the side effects and dangers of the medications before we take them. Keep in mind that drug companies are in business to make money and that they would say anything to keep people on the medications.
Researchers found that participants investing in this drug for any year, dropped a few pounds within 4 weeks and have kept the weight off through the entire 56 weeks of the study. Contrave is a combination of the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which might be made up of several active ingredient, which might make them more efficient and safer.
Combo-pilling is the newest fad or even better the newest to come under scrutiny and thus it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular may be the fact that by right now there aren't any long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be authorized by the FDA.
Seizures are a side effect with Contrave and really should not be taken in people with seizure disorders. The drug may also raise blood pressure level and heartrate, and really should not be used in those with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug.
The FDA also warned that Contrave can raise blood pressure level and pulse rate and must stop used in patients with uncontrolled high blood pressure levels, as well as by you aren't heart-related and cerebrovascular (blood vessel dysfunction impacting the mind) disease. Patients with a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients on the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking.
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